[vc_row type=”in_container” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” overflow=”visible” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none”][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_column_text text_direction=”default”]You may have come across references to H4CBD online – a hydrogenated cannabinoid that is sometimes described as hundreds of times more potent than CBD. In this article, we’ll take a closer look at this new species. If you’re wondering what H4CBD is, what effects it has, and how it compares to CBD, you’re in the right place.
What is H4CBD?
H4CBD is a cannabinoid created by synthetic modification of CBD. This cannabinoid is a derivative of CBD, meaning that four hydrogen atoms have been added to the CBD molecule. How is H4CBD produced? Simply put, we can liken the production process to the way margarine is made from vegetable oil. H4CBD or THD is a derivative of CBD that is produced in the lab or semi-synthetically. Also known as hydrogenated CBD, this cannabinoid was created as an alternative form of conventional CBD. Scientists have been researching and developing semi-synthetic and synthetic cannabinoids since the mid-20th century.
How does H4CBD work?
H4CBD is still “in its infancy”, i.e. it remains a relatively unexplored cannabinoid, but the little information about it suggests that it has an affinity for CB1 neuroreceptors. H4CBD is actually a modified version of CBD, but with the difference that it affects the brain. The effects are similar to HHC, but H4CBD does not contain a double bond. H4CBD consists of two diastereomers, R and S, with the R diastereomer having significantly stronger effects than the S diastereomer. Users of H4CBD described their experience comparing the effects to CBD, but reported having additional psychoactive effects.
Is H4CBD the same as CBD?
The answer is “No”. Although both cannabinoids share certain properties, they are different molecules. For example, they have completely different effects and the fundamental differences lie in their chemical structures and production methods.
What is the comparison between H4CBD and HHC?
H4CBD and HHC are different substances, although their origin is similar. HHC is the hydrogenated version of THC, while H4CBD is the hydrogenated version of CBD. Each is based on different basic molecules. This difference also results in different effects on the body.
Comparison: H4CBD with CBD
CBD and H4CBD have a lot in common, but they also differ in many ways. How do these two cannabinoids compare? Take a look at the categories below.
1. Source
Both CBD and H4CBD are derived from hemp. CBD is a direct derivative of cannabis, while H4CBD undergoes a transformation process, including hydrogenation, to reach its final form. Because of this, H4CBD is considered a synthetic cannabinoid. Technically, it is also possible to synthesise CBD. However, there is no need to do so, as this cannabinoid is abundant in cannabis.
2. Structure
H4CBD has been structurally modified to take a different form from CBD. This is a chemical process that introduces hydrogen atoms into the selected molecule. Four additional hydrogen atoms are added to the molecule, altering its physical properties.
3. Effects of H4CBD
If we look at a single study from 2006, we find that the study says that hydrogenated forms of CBD have extremely high affinity with the brain’s CB1 neuroreceptors. It’s this finding that has expanded speculation that H4CBD may have effects up to a hundred times greater than CBD – at least in some ways. A research review from 2017 confirmed this hypothesis, but no new studies have been conducted on the bioactive properties of H4CBD.
4. Action
H4CBD is reported to offer 100 times more potency than regular CBD. However, we have already learned that even though this is the case, it only applies to the potency of CBD at CB1 receptors. And this efficacy was originally negligible for CBD. H4CBD at CB1 receptors requires further research to draw conclusions related to possible increased activity. Therefore, to state that H4CBD is “100 times more potent” than CBD across the board is a rather exaggerated claim. H4CBD can be seen as an improved alternative with higher potency, while CBD offers a natural variant with lower potency. As modern cannabinoid medicine continues to evolve, both CBD and H4CBD will undoubtedly play key roles.[/vc_column_text][/vc_column][/vc_row]
